Short Communication: Ethnobotanical survey of medicinal plants for wound healing in Dir Upper District, Pakistan
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Abstract. Jawadullah, Akhtar N. 2023. Short Communication: Ethnobotanical survey of medicinal plants for wound-healing in Dir Upper District, Pakistan. Asian J Ethnobiol 6: 145-152. Medicinal plants have been used since ancient time by the communities as an alternative to the synthetic medicine, which have adverse side effects and is not available to every individual. This study reports medicinal plants used for wound-healing by the local peoples in Dir Upper District, northern area of Pakistan. A semi-structured questionnaire was used to collect ethnomedicinal data by interviewing 50 informants of different ages (25 to 90 years old). Plant samples were collected as herbarium to be identified in the laboratory. The result shows a total of 20 plant species, each belonging to different families, were used for wound-healing. The majority of growth forms of such plants were herbs (35%) and trees (35%), followed by shrubs (25%) and climbers (5%). The plant parts used for healing were leaves of the plant (45%), followed by plant bark (10%), whole plant (10%), plant roots (10%), fruit peel (5%), gum (5%), bulb (5%), rhizome (5%) and latex (5%). Furthermore, external applications were more common than oral consumption to promote wound-healing. Berberis lycium Royle, Curcuma longa L. and Punica protopunica Balf.fil. were the most cited species used to heal wounds. This study revealed that there is an array of plant biodiversity among Pakistanis for the purpose of wound-healing. This is a result of the socioeconomic status and limited access to modern health services and their preference for folk medicine. Further studies should be planned to create an online database for a collection of therapeutic medicinal plants and their traditional healing potentials.
2018-01-01
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References
Abbasi AM, Khan MA, Ahmad M, Zafar M, Jahan S, Sultana S. 2010. Ethnopharmacological application of medicinal plants to cure skin diseases and in folk cosmetics among the tribal communities of North-West Frontier Province, Pakistan. J Ethnopharmacol 128 (2): 322-335. DOI: 10.1016/j.jep.2010.01.052.
Alam G, Singh MP, Singh A. 2011. Wound-healing potential of some medicinal plants. Intl J Pharm Sci Rev Res 9 (1): 136-145.
Albahri G, Badran A, Hijazi A, Daou A, Baydoun E, Nasser M, Merah O. 2023. The therapeutic wound-healing bioactivities of various medicinal plants. Life 13 (2): 317. DOI: 10.3390/life13020317.
Ayyanar M, Ignacimuthu S. 2009. Herbal medicines for wound-healing among tribal people in Southern India: Ethnobotanical and scientific evidences. Intl J Appl Res Nat Prod 2 (3): 29-42.
Azad AK, Mahmud MR, Parvin A, Chakrabortty A, Akter F, Moury SI, Akter S, Rahmatullah M. 2014. Medicinal plants of a Santal tribal healer in Dinajpur District, Bangladesh. World J Pharm Pharmaceut Sci 3 (10): 1597-1606.
Bhardwaj S, Gakhar SK. 2005. Ethnomedicinal plants used by the tribals of Mizoram to cure cuts & wounds. Indian J Tradit Knowl 4 (1): 75-80.
Bhattarai NK. 1997. Traditional herbal medicines used to treat wounds and injuries in Nepal. Trop Doct 27 (1): 43-47. DOI: 10.1177/00494755970270S114.
Birhan YS, Kitaw SL, Alemayehu YA, Mengesha NM. 2023. Medicinal plants with traditional healthcare importance to manage human and livestock ailments in Enemay District, Amhara Region, Ethiopia. Acta Ecologica Sinica 43 (2): 382-399. DOI: 10.1016/j.chnaes.2022.05.004.
Budovsky A, Yarmolinsky L, Ben?habat S. 2015. Effect of medicinal plants on wound-healing. Wound Repair Regen 23 (2): 171-183. DOI: 10.1111/wrr.12274.
Bukhari SMF, Ali G. 2022. An overview of ethnobotany of Berberis lycium Royle in Pakistan. In: Öztürk M, Khan SM, Altay V, Efe R, Egamberdieva D, Khassanov FO (eds). Biodiversity, Conservation and Sustainability in Asia: Volume 2: Prospects and Challenges in South and Middle Asia. Springer, Cham. DOI: 10.1007/978-3-030-73943-0.
Cheikhyoussef A, Shapi M, Matengu K, Ashekele HM. 2011. Ethnobotanical study of indigenous knowledge on medicinal plant use by traditional healers in Oshikoto region, Namibia. J Ethnobiol Ethnomed 7 (1): 10. DOI: 10.1186/1746-4269-7-10.
Criollo-Mendoza MS, Contreras-Angulo LA, Leyva-López N, Gutiérrez-Grijalva EP, Jiménez-Ortega LA, Heredia JB. 2023. Wound-healing properties of natural products: Mechanisms of action. Molecules 28 (2): 598. DOI: 10.3390/molecules28020598.
Grierson DS, Afolayan AJ. 1999. An ethnobotanical study of plants used for the treatment of wounds in the Eastern Cape, South Africa. J Ethnopharm 67 (3): 327-332. DOI: 10.1016/S0378-8741(99)00082-3.
Guzo S, Lulekal E, Nemomissa S. 2023. Ethnobotanical study of underutilized wild edible plants and threats to their long-term existence in Midakegn District, West Shewa Zone, Central Ethiopia. J Ethnobiol Ethnomed 19 (1): 30. DOI: 10. 1186/s13002-023-00601-8.
Handoo S. 2006. A survey of plants used for wound-healings in animals. Vet Scan 1 (1): 3-9. DOI: 10.1186/1751-0147-1-3.
Inngjerdingen K, Nergård CS, Diallo D, Mounkoro PP, Paulsen BS. 2004. An ethnopharmacological survey of plants used for wound-healing in Dogonland, Mali, West Africa. J Ethnopharmacol 92 (2-3): 233-244. DOI: 10.1016 /j. jep. 2004.02.021.
Jari? S, Kosti? O, Mataruga Z, Pavlovi? D, Pavlovi? M, Mitrovi? M, Pavlovi? P. 2018. Traditional wound-healing plants used in the Balkan region (Southeast Europe). J Ethnopharmacol 211: 311-328. DOI: 10.1016/j.jep.2017.09.018.
Khan IA, Din MMU, Hussain S, Akbar R, Saeed M, Farid A, Fayaz W, Shah RA. 2015. A study of mosquito fauna of District Upper Dir, Khyber Pakhtunkhwa-Pakistan. J Entomol Zool Stud 3 (5): 455-458.
Kumar B, Vijayakumar M, Govindarajan R, Pushpangadan P. 2007. Ethnopharmacological approaches to wound-healing—exploring medicinal plants of India. J Ethnopharmacol 114 (2): 103-113. DOI: 10.1016/j.jep.2007.08.010.
Marques MP, Mendonça L, Neves BG, Varela C, Oliveira P, Cabral C. 2023. Exploring Iberian Peninsula Lamiaceae as potential therapeutic approaches in wound-healing. Pharmaceuticals 16 (3): 347. DOI: 10.3390/ph16030347.
Mobale MM, Ngbolua KTNJP, Djamba AM, Jeannine EM, Mawunu M, Ashande CM, Mpiana PT. 2023. Survey on wound-healing plants traditionally used by the bambenga pygmy indigenous peoples of Dongo Sector (South Ubangi Province) in the Democratic Republic of The Congo. Egypt Acad J Biol Sci 14 (1): 29-42. DOI: 10.21608/EAJBSH.2023.287751.
Monika P, Chandraprabha MN, Rangarajan A, Waiker PV, Chidambara Murthy KN. 2022. Challenges in healing wound: Role of complementary and alternative medicine. Front Nutr 8: 791899. DOI: 10.3389/fnut.2021.791899.
Mssillou I, Bakour M, Slighoua M, Laaroussi H, Saghrouchni H, Amrati FEZ, Lyoussi B, Derwich E. 2022. Investigation on wound-healing effect of Mediterranean medicinal plants and some related phenolic compounds: A review. J Ethnopharmacol 298: 115663. DOI: 10.1016/j.jep.2022.115663.
Muhammad I, Hasan Z, Ullah S, Ullah W, Ullah H. 2014. A preliminary survey of fish fauna of river Panjkora at District Upper Dir, Khyber Pakhtunkhwa Pakistan. J Biodivers Environ Sci 5 (1): 362-368.
Muthu C, Ayyanar M, Raja N, Ignacimuthu S. 2006. Medicinal plants used by traditional healers in Kancheepuram District of Tamil Nadu, India. J Ethnobiol Ethnomed 2 (1): 43. DOI: 10.1186/1746-4269-2-43.
Neto JAR, Tarôco BRP, dos Santos HB, Thomé RG, Wolfram E, Ribeiro RIMDA. 2020. Using the plants of Brazilian Cerrado for wound-healing: From traditional use to scientific approach. J Ethnopharmacol 260: 112547. DOI: 10.1016/j.jep.2020.112547.
Oguntibeju OO. 2019. Medicinal plants and their effects on diabetic wound-healing. Vet World 12 (5): 653-663. DOI: 10.14202/vetworld.2019.653-663.
Pirbalouti AG, Koohpayeh A, Karimi I. 2010. The wound-healing activity of flower extracts of Punica granatum and Achillea kellalensis in Wistar rats. Acta Pol Pharm 67 (1): 107-10.
Sharma A, Khanna S, Kaur G, Singh I. 2021. Medicinal plants and their components for wound-healing applications. Future J Pharm Sci 7 (1): 1-13. DOI: 10.1186/s43094-021-00202-w.
Shedoeva A, Leavesley D, Upton Z, Fan C. 2019. Wound-healing and the use of medicinal plants. Evid Based Complement Alternat Med 2019: 2684108. DOI: 10.1155/2019/2684108.
Tahir M, Asnake H, Beyene T, Van Damme P, Mohammed A. 2023. Ethnobotanical study of medicinal plants in Asagirt District, Northeastern Ethiopia. Trop Med Health 51 (1): 1-13. DOI: 10.1186/s41182-023-00493-0.
Venkatesh S, Reddy YR, Ramesh M, Swamy MM, Mahadevan N, Suresh B. 2008. Pharmacognostical studies on Dodonaea viscosa leaves. Afr J Pharm Pharmacol 2 (4): 083-088.
Xu Z, Dong M, Yin S, Dong J, Zhang M, Tian R, Min W, Zeng L, Qiao H, Chen J. 2023. Why traditional herbal medicine promotes wound-healing: Research from immune response, wound microbiome to controlled delivery. Adv Drug Deliver Rev 195: 114764. DOI: 10.1016/j.addr.2023.114764.
Yazarlu O, Iranshahi M, Kashani HRK, Reshadat S, Habtemariam S, Iranshahy M, Hasanpour M. 2021. Perspective on the application of medicinal plants and natural products in wound-healing: A mechanistic review. Pharmacol Res 174: 105841. DOI: 10.1016/j.phrs.2021.105841.
Zulkefli N, Che Zahari CNM, Sayuti NH, Kamarudin AA, Saad N, Hamezah HS, Bunawan H, Baharum SN, Mediani A, Ahmed QU, Ismail AFH, Sarian MN. 2023. Flavonoids as potential wound-healing molecules: Emphasis on pathways perspective. Int J Mol Sci 24 (5): 4607. DOI: 10.3390/ijms24054607.