Chemotypes and antibacterial activities of Inula viscosa essential oils from Algeria
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Abstract. Ounoughi A, Ramdani M, Lograda T, Chalard P, Figueredo G. 2020. Chemotypes and antibacterial activities of Inula viscosa essential oils from Algeria. Biodiversitas 21: 1504-1517. The aim of this work is to investigate the chemical composition and the antibacterial activities of the essential oils from Inula viscosa (L.) Aiton. Samples were collected in the flowering stage, from different localities in Algeria. The aerial parts of I. viscosa were submitted to a hydro distillation. The chemical composition of the essential oil was analyzed by GC and GC/MS. The antibacterial activity of the essential oils was evaluated using the disc diffusion method against fifteen bacterial species. Fifty-eight compounds representing 98.93 ± 2.03% of the total oil was identified in I. viscosa. It was found that the chemical composition was dominated by the presence of the following major products: polygodial (19.8 ± 16.97%), phytol (12.3 ± 9.77%), fokienol (6.01 ± 3.43%), intermedeol neo (5.09 ± 2.38%), caryophyllene oxide (4.91 ± 3.03%), nerolidol-Z (4.46 ± 5.46%), nerolidol-E (4.24 ± 8.07%) and ?-ionone iso methyl-E (3.72 ± 2.26%). The essential oil of I. viscosa has moderate activity against the bacteria tested. In contrast, the Escherichia coli ATCC 25922, Pseudomonon syringae ATCC 53543 and Enterococcus faecalis ATCC 49452 strains are resistant to I. viscosa essential oils. The phytochemical study of I. viscosa showed that it is rich in terpene compounds, with polygodial and phytol as major components. Three distinct chemotypes are highlighted. The (Polygodial-Intermedeol-neo-Phytol) chemotype of Salah Bey population and two chemotypes with Fokinol-polygodial and Fokinol-phytol. Moderate antibacterial activities of essential oils against the bacteria tested were found.
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Al-Masri Mohammad I, Sharawi Sahar M, Barakat Radwan M. 2015. Effect of Clammy Inula (Inula viscosa) Plant Extract in Combination with a Low Dose of the Fungicide Iprodione on Botrytis cinerea in Vitro and in Vivo. American Journal of Plant Sciences 6: 1519-1526. http://dx.doi.org/10.4236/ajps.2015.69151
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Andol? Anna, Nadjia Zermane, Alessio Cimmino, Fabiana Avolio, Angela Boari, Antonio Evidente, Maurizio Vurro. 2013. Inuloxins A–D. phytotoxic bi-and tricyclic sesquiterpene lactones produced by Inula viscosa: Potential for broomrapes and ?eld dodder management. Phytochemistry 86: 112-120. https://doi.org/10.1016/j.phytochem.2012.10.003
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Belayachi L, Aceves-Luquero C, Merghoub N, Bakri Y, Fernández de Mattos S, Amzazi Sand PV. 2013. Screening of North African Medicinal Plant Extracts for Cytotoxic Activity A gainst Tumor Cell Lines, European Journal of Medicinal Plants 3(3): 310-332. http://journalejmp.com/index.php/EJMP/article/view/14087/25874
Benseguini-Tounsi L. 2001. Etude in vitro de l’effet antibactérien et antifongiques d’Inula Viscosa, Lawsonia inermis, Asphodelus microcarpus, Aloe vera et Juniperus oxycedrus. Mémoire de magistère en médecine vétérinaire. Université de Constantine. 110p. https://bu.umc.edu.dz/theses/veterinaire/BEN4392.pdf
Berhail Boudouda H, Benmerache Semra ZA, Chibani S, Kabouche Z, Kabouche A, Abuhamdah S. 2012. Antibacterial Activity and Chemical Composition of Essential Oils of Inula viscosa (L.) Ait. (Asteraceae) from Constantine. Algeria. Der Pharmacia Lettre 4(6): 1878-1882. http://scholarsresearchlibrary.com/archive.html
Berhail Boudouda houria. 2014. Etude phytochimique et biologique des espèces Biscutella raphanifolia, Zilla macroptera, Inula graveolens et Inula viscosa, thèse Doctorat trois?me cycle (LMD), Université de Constantine 1. https://bu.umc.edu.dz/theses/chimie/BER6586.pdf
Blanc MC, Bradesi P, Gonçalves MJ, Salgueiro L, Casanova J. 2006. Essential oil of Dittrichia viscosa spp. viscosa: analysis by 168 C-NMR and antimicrobial activity. Flav Fragr J. 21: 324-332. https://doi.org/10.1002/ffj.1605
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