Ethnopharmacology of medicinal plants used by the Tenggerese community in Bromo Tengger Semeru National Park, Indonesia
##plugins.themes.bootstrap3.article.sidebar##
Issue
Section
Articles
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
##plugins.themes.bootstrap3.article.main##
Abstract
Abstract. Bhagawan WS, Ekasari W, Agil M. 2023. Ethnopharmacology of medicinal plants used by the Tenggerese community in Bromo Tengger Semeru National Park, Indonesia. Biodiversitas 24: 5464-5477. Bromo Tengger Semeru National Park is a repository of biodiversity with profound cultural significance. The Tenggerese community residing within the park possesses rich ethnopharmacological knowledge, using medicinal plants for various ailments. This study aims to comprehensively explore the medicinal plant diversity, traditional uses, and potential pharmacological activities among the Tenggerese people. Ethnopharmacological data was gathered through interviews with informants in seven Tenggerese villages. Ethnopharmacological indices like Species Use Value (SUV) and Fidelity Level (FL) were calculated to identify the most important medicinal plants. Phytochemical analysis of selected medicinal plants was conducted using UPLC-QTOF-MS/MS, and its pharmacological potential was assessed through antibacterial tests. A total of 124 medicinal plant species from 54 families were documented. The Tenggerese community utilizes plants to treat diverse diseases, with reproductive healthcare being prominently featured. Elaeocarpus longifolius emerged as a key species with high SUV and FL values. Phytochemical analysis identified 25 compounds, including major and minor compounds, already known for their pharmacological activities elsewhere. Elaeocarpus longifolius extract showed inhibitor activity against both gram-positive and gram-negative bacteria. The findings contribute to bridging traditional knowledge and modern scientific research, offering potential avenues for the development of drug candidates from indigenous medicinal plants.
##plugins.themes.bootstrap3.article.details##
References
Abbas Z, Kousar S, Aziz MA, Pieroni A, Aldosari AA, Bussmann RW, Raza G, Abbasi AM. 2021. Comparative assessment of medicinal plant utilization among balti and shina communities in the periphery of deosai national park, pakistan. Biology (Basel). 10. DOI: 10.3390/biology10050434.
Abou-ghadir OF, Hayallah AM, Abdel-moty SG, Hussein MA. 2014. Design and synthesis of some new purine-dione derivatives of potential anti- inflammatory activity Design and synthesis of some new purine-dione derivatives of potential anti-inflammatory activity. Der Pharma Chem. 6, 199–211.
Amri J, El Badaoui K, El Zair T, Bouharb H, Chakir S, Alaoui TEM. 2014. Ethnobotanical study of medicinal plants in the region El Hajeb (Central Morocco). J. Res. Biol. 4, 1568–1580.
Arbiastutie Y, Marsono D, Hartati MS, Purwanto R. 2017. The potential of understorey plants from Gunung Gede Pangrango National Park (West Java, Indonesia) as cervixs anticancer agents. Biodiversitas 18, 109–115. DOI: 10.13057/biodiv/d180116.
Aswani S, Lemahieu A, Sauer WHH. 2018. Global trends of local ecological knowledge and future implications. PLoS One 13, 1–19. DOI: 10.1371/journal.pone.0195440
Athayde S, Silva-Lugo J, Schmink M, Heckenberger M. 2017. The same, but different: Indigenous knowledge retention, erosion, and innovation in the Brazilian Amazon. Hum. Ecol. 45, 533–544. DOI: 10.1007/s10745-017-9919-0.
Aziz Y, Peranginangin J, Sunarni T. 2019. Ethnomedicin studies and antimicrobial activity tests of plants used in the Tengger Tribal Community, in: 1st International Conference of Health, Science & Technology (ICOHETECH). pp. 160–164.
Balouiri M, Sadiki M, Ibnsouda SK. 2016. Methods for in vitro evaluating antimicrobial activity: A review. J. Pharm. Anal. 6, 71–79. DOI: 10.1016/j.jpha.2015.11.005.
Barkaoui M, Katiri A, Boubaker H, Msanda F. 2017. Ethnobotanical survey of medicinal plants used in the traditional treatment of diabetes in Chtouka Ait Baha and Tiznit (Western Anti-Atlas), Morocco. J. Ethnopharmacol. 198, 338–350. DOI: 10.1016/j.jep.2017.01.023.
Batoro J. 2017. Keajaiban Bromo Tengger Semeru: Analisis Kehidupan Suku Tengger-Antropologi-Biologi di Lingkungan Bromo Tengger Semeru Jawa Timur. Universitas Brawijaya Press. [Indonesian]
Batoro J, Siswanto D. 2017. Ethnomedicinal survey of plants used by local society in Poncokusumo district, Malang, East Java Province, Indonesia. Asian J. Med. Biol. Res. 3, 158–167. DOI: 10.3329/ajmbr.v3i2.33563
Bhagawan WS, Aziz YS, Pamungkas RPT. 2020. Pendekatan etnofarmasi tumbuhan obat imunomodulator suku Tengger, Desa Ngadas, Kabupaten Malang, Indonesia. J. Islam. Med. 4, 98–105. DOI: 10.18860/jim.v4i2.10290. [Indonesian]
Bhagawan WS, Barsyaif UA, Amrun M. 2021. Pendekatan etnobotani tumbuhan obat untuk permasalahan seksual suku Tengger di Desa Argosari, Lumajang, Indonesia. J. Tumbuh. Obat Indones. 14, 99–110. DOI: 10.22435/jtoi.v14i2.4169. [Indonesian]
Bhagawan WS, Kusumawati D. 2021. Ethnobotanical medicinal plant study of Tengger tribe in Ranu Pani Village, Indonesia. SSRN Electron. J. DOI: 10.2139/ssrn.3865725.
Bhagawan WS, Ekasari W, Agil M. 2023. Education system and traditional knowledge of medicinal plants for healthcare in Tengger tribe, Argosari Village, East Java, Indonesia. 3rd ICETECH 2022-Atlantis Press. DOI: 10.2991/978-2-38476-056-5_76.
Bhagawan WS, Suproborini A, Putri DLP, Nurfatma A, Putra RT. 2022. Ethnomedicinal study, phytochemical characterization, and pharmacological confirmation of selected medicinal plant on the northern slope of Mount Wilis, East Java, Indonesia. Biodiversitas J. Biol. Divers. 23, 4303–4313. DOI: 10.13057/biodiv/d230855.
Bischoff-Kont I, Fürst R. 2021. Benefits of ginger and its constituent 6-Shogaol in inhibiting inflammatory processes. Pharmaceuticals 14, 1–19. DOI: 10.3390/ph14060571.
CLSI. 2012. Performance standards for antimicrobial disk susceptibility tests: Approved standard, 11th ed. Clinical and Laboratory Standards Institute, Pennsylvania, USA. DOI: M02-A11.
De Koning TJ, Snell K, Duran M, Berger R, Poll-The BT, Surtees R. 2003. L-serine in disease and development. Biochem. J. 371, 653–661. DOI: 10.1042/BJ20021785.
Derosa G, Maffioli P, Sahebkar A. 2016. Piperine and Its Role in Chronic Diseases, in: Anti-Inflammatory Nutraceuticals and Chronic Diseases. Springer, pp. 173–184. DOI: 10.1007/978-3-319-41334-1_8.
Duan X, Huang X, Wang X, Yan S, Guo S, Abdalla AE, Huang C, Xie J. 2016. L-Serine potentiates fluoroquinolone activity against Escherichia coli by enhancing endogenous reactive oxygen species production. J. Antimicrob. Chemother. 71, 2192–2199. DOI: 10.1093/jac/dkw114.
Elliott S, Brimacombe J. 1987. The medicinal plants of Gunung Leuser National Park, Indonesia. J. Ethnopharmacol. 19, 285–317. DOI: 10.1016/0378-8741(87)90006-7.
Ferretti-Gallon K, Griggs E, Shrestha A, Wang G. 2021. National parks best practices: Lessons from a century’s worth of national parks management. Int. J. Geoheritage Park. 9, 335–346. DOI: 10.1016/j.ijgeop.2021.05.004.
Friedman, J., Yaniv, Z., Dafni, A., Palewitch, D., 1986. A preliminary classification of the healing potential of medicinal plants, based on a rational analysis of an ethnopharmacological field survey among Bedouins in the Negev Desert, Israel. J. Ethnopharmacol. 16, 275–287. DOI: 10.1016/0378-8741(86)90094-2.
Gailea R, Bratawinata A, Pitopang R, Kusuma I. 2016. The use of various plant types as medicines by local community in the enclave of the Lore-Lindu National Park of Central Sulawesi, Indonesia. Glob. J. Res. Med. Plants Indig. Med. || GJRMI || 5, 29–40.
Gumisiriza H, Birungi G, Olet EA, Sesaazi CD. 2019. Medicinal plant species used by local communities around Queen Elizabeth National Park, Maramagambo Central Forest Reserve and Ihimbo Central Forest Reserve, South Western Uganda. J. Ethnopharmacol. 239, 111926. DOI: 10.1016/j.jep.2019.111926.
Haq I, Imran M, Nadeem M, Tufail T, Gondal TA, Mubarak MS. 2020. Piperine: A review of its biological effects. Phyther. Res. 1–21. DOI: 10.1002/ptr.6855.
Heinrich M, Jager AK. 2015. Ethnopharmacology. John Wiley & Sons Ltd, Oxford, UK.
Hua X, Liu W, Chen Y, Ru J, Guo S, Yu X, Cui Y, Liu X, Gu Y, Xue C, Liu Y, Sui J, Wang G. 2021. Synthesis, fungicidal activity, and mechanism of action of pyrazole amide and ester derivatives based on natural products L-Serine and waltherione alkaloids. J. Agric. Food Chem. 69, 11470–11484. DOI: 10.1021/acs.jafc.1c01346.
Huda MT, Khasanah I. 2019. The relationship between religious tribes in Tengger (Hindu, Islam and Budha). Vidyottama Sanatana Int. J. Hindu Sci. Relig. Stud. 3, 284. DOI: 10.25078/ijhsrs.v3i2.748.
Husaini IPA, Maulany RI, Nasri N, Ngakan PO. 2022. Diversity and use of traditional medicinal plant species in Bantimurung-Bulusaraung National Park, Indonesia. Biodiversitas 23, 5539–5550. DOI: 10.13057/biodiv/d231101.
International Society of Ethnobiology. 2006. ISE Code of Ethics (with 2008 additions).
Jadid N, Kurniawan E, Himayani CES, Andriyani, Prasetyowati I, Purwani KI, Muslihatin W, Hidayati D, Tjahjaningrum ITD. 2020. An ethnobotanical study of medicinal plants used by the Tengger tribe in Ngadisari village, Indonesia. PLoS One 15, e0235886. DOI: 10.1371/journal.pone.0235886.
Jamshidi-Kia F, Lorigooini Z, Amini-Khoei H. 2018. Medicinal plants: Past history and future perspective. J. HerbMed Pharmacol. 7, 1–7. DOI: 10.15171/jhp.2018.01.
Jufe-Bignoli D, Burgess N, Bingham H, Belle E, de Lima M, Deguignet M, Bertzky B, Milam A, Martinez-Lopez J, Lewis E, Eassom A, Wicander S, Geldmann J, van Soesbergen A, Arnell A, O’Connor B, Park S, Shi Y, Danks F, MacSharry B, Kingston N. 2014. Protected Planet Report 2014. UNEP-WCMC, Cambridge, UK.
Kayani S, Ahmad M, Sultana S, Khan Shinwari Z, Zafar M, Yaseen G, Hussain M, Bibi T. 2015. Ethnobotany of medicinal plants among the communities of Alpine and Sub-alpine regions of Pakistan. J. Ethnopharmacol. 164, 186–202. DOI: 10.1016/j.jep.2015.02.004.
Kim H, Song MJ. 2014. Analysis of traditional knowledge about medicinal plants utilized in communities of Jirisan National Park (Korea). J. Ethnopharmacol. 153, 85–89. DOI: 10.1016/j.jep.2013.10.047.
Kou X, Wang X, Ji R, Liu L, Qiao Y, Lou Z, Ma C, Li S, Wang H, Ho C. 2018. Occurrence, biological activity and metabolism of 6-shogaol. Food Funct. 9, 1310–1327. DOI: 10.1039/C7FO01354J.
Laksmiani N, Widiastari M, Reynaldi K. 2017. The inhibitory activity of peonidin purple sweet potato in human epidermal receptor-2 receptor (her-2) expression by in silico study. J. Phys. Conf. Ser. 1040, 1–5. DOI: 10.1088/1742-6596/1040/1/012010.
Laksono AD. 2020. Tengger Bertahan dalam Adat: Studi Konstruksi Sosial Ukuran Keluarga Suku Tengger. Health Advocacy, Surabaya. [Indonesian]
Lee S, Ding Y, Yan XT, Kim Y, Jang H. 2013. Scopoletin and scopolin isolated from Artemisia iwayomogi suppress differentiation of osteoclastic macrophage RAW 264.7 cells by scavenging reactive oxygen species. J. Nat. Prod. 76, 615–620. DOI: 10.1021/np300824h.
Mahmoud WH, Fatma MMO, Gehad NS. 2018. Synthesis, characterization, spectroscopic, and theoretical studies of transition metal complexes of new nano schiff base derived from L?histidine and 2?acetylferrocene and evaluation of biological and anticancer activities. Appl. Organomet. Chem. e4386, 1–18. DOI: 10.1002/aoc.4386.
Maralani MN, Movahedian A, Javanmard SH. 2012. Antioxidant and cytoprotective effects of L-serine on human endothelial cells. Res. Pharm. Sci. 7, 209–215.
Maugard M, Vigneron PA, Bolaños JP, Bonvento G. 2021. L-Serine links metabolism with neurotransmission. Prog. Neurobiol. 197. DOI: 10.1016/j.pneurobio.2020.101896.
Meghwal M, Goswami TK. 2013. Piper nigrum and piperine?: An update. Phyther. Res. 27, 1121–1130. DOI: 10.1002/ptr.4972.
Nugraha AS, Agustina RP, Mirza S, Rani DM, Winarto NB, Triatmoko B, Pratama ANW, Keller PA, Wangchuk P. 2022. Phytochemistry and pharmacology of medicinal plants used by the Tenggerese society in Java Island of Indonesia. Molecules 27. DOI: 10.3390/molecules27217532.
Nugraha AS, Permatasari AEN, Kadarwenny CP, Pratoko DK, Triatmoko B, Rosyidi VA, Norcahyanti I, Dewi IP, Dianasari D, Sary IP, Wangchuk P. 2020. Phytochemical screening and the antimicrobial and antioxidant activities of medicinal plants of Meru Betiri National Park–Indonesia. J. Herbs, Spices Med. Plants 26, 303–314. DOI: 10.1080/10496475.2020.1734136.
Nurrochmat DR, Nugroho IA, Hardjanto, Purwadianto A, Maryudi A, Erbaugh JT. 2017. Shifting contestation into cooperation: Strategy to incorporate different interest of actors in medicinal plants in Meru Betiri National Park, Indonesia. For. Policy Econ. 83, 162–168. DOI: 10.1016/j.forpol.2017.08.005.
Ong HG, Ling SM, Win TTM, Kang DH, Lee JH, Kim YD. 2018. Ethnomedicinal plants and traditional knowledge among three Chin indigenous groups in Natma Taung National Park (Myanmar). J. Ethnopharmacol. 225, 136–158. DOI: 10.1016/j.jep.2018.07.006.
Ooi SL, Campbell R, Hons B, Pak SC, Golombick T, Manoharan A, Ramakrishna R. 2021. Is 6-Shogaol an effective phytochemical for patients with lower-risk myelodysplastic syndrome?? A narrative review. Integr. Cancer Ther. 20, 1–12. DOI: 10.1177/15347354211065038.
Park E, Kim J, Jin HS, Choi CW, Choi TH, Choi S, Huh D, Jeong SY. 2020. Scopolin attenuates osteoporotic bone loss in ovariectomized mice. Nutrients 12, 1–14. DOI: 10.3390/nu12113565.
Pepi MJ, Chacko S, Kopetz N, Boshoff HIM, Cuny GD, Hedstrom L. 2023. Nonhydrolyzable d?phenylalanine-benzoxazole derivatives retain antitubercular activity. Bioorg. Med. Chem. Lett. 80, 129116. DOI: 10.1016/j.bmcl.2022.129116.
Pepi MJ, Chacko S, Marqus GM, Singh V, Wang Z, Planck K, Cullinane RT, Meka PN, Gollapalli DR, Ioerger TR, Rhee KY, Cuny GD, Boshoff HIM, Hedstrom L. 2022. A d-phenylalanine-benzoxazole derivative reveals the role of the essential enzyme Rv3603c in the pantothenate biosynthetic pathway of Mycobacterium tuberculosis. ACS Infect. Dis. 8, 330–342. DOI: 10.1021/acsinfecdis.1c00461.
Phillips O, Gentry AH. 1993a. The useful plants of Tambopata, Peru: I. Statistical hypotheses tests with a new quantitative technique. Econ. Bot. 47, 15–DOI: 10.1007/BF02862203.
Phillips O, Gentry AH. 1993b. The useful plants of Tambopata, Peru: II. Additional hypothesis testing in quantitative ethnobotany. Econ. Bot. 47, 33–43. DOI: 10.1007/BF02862204.
Putri F, Noven H, Nurcahyati M, Irfan A, Septiasari A, Batoro J, Setyawan A. 2022. Review: Local wisdom of the Tengger tribe, East Java, Indonesia in environmental conservation. Asian J. Ethnobiol. 5, 20–34. DOI: 10.13057/asianjethnobiol/y050203.
Rahaman M, Tanim TI, Islam MT. 2023. A short review on 6-Shogaol. Clin. Res. Notes 4, 4–7. DOI: 10.31579/2690-8816/078.
Rathgeb A, Böhm A, Novak MS, Gavriluta A, Dömötör O, Tommasino JB., Enyedy ÉA, Shova S, Meier S, Jakupec MA, Luneau D, Arion VB. 2014. Ruthenium-nitrosyl complexes with Glycine, L?Alanine, L?Valine, L?Proline, D?Proline, L?Serine, L?Threonine, and L?Tyrosine: Synthesis, x?ray diffraction structures, spectroscopic and electrochemical properties, and antiproliferative activity. Inorg. Chem. 53, 2718–2729. DOI: 10.1021/ic4031359.
Ratnadewi AAI, Wahyudi LD, Rochman J, Susilowati, Nugraha AS, Siswoyo TA. 2020. Revealing anti-diabetic potency of medicinal plants of Meru Betiri National Park, Jember – Indonesia. Arab. J. Chem. 13, 1831–1836. DOI: 10.1016/j.arabjc.2018.01.017.
Redouan FZ, Benítez G, Picone RM, Crisafulli A, Yebouk C, Bouhbal M, Ben Driss A, Kadiri M, Molero-Mesa J, Merzouki A. 2020. Traditional medicinal knowledge of Apiaceae at Talassemtane National Park (Northern Morocco). South African J. Bot. 131, 118–130. DOI: 10.1016/j.sajb.2020.02.004.
Roli OI, Adetunji CO, Mishra RR, Adetunji JB, Mishra P. 2020. Rediscovering Medicinal Activity and Food Significance of Shogaol (4, 6, 8, 10, and 12): Comprehensive Review, in: Innovations in Food Technology. Springer Singapore, pp. 125–145. DOI: 10.1007/978-981-15-6121-4_9.
Ruszkiewicz J, Albrecht J. 2015. Changes of the thioredoxin system, glutathione peroxidase activity and total antioxidant capacity in rat brain cortex during acute liver failure: Modulation by L -histidine. Neurochem. Res. 40, 293–300. DOI: 10.1007/s11064-014-1417-9.
Sadat S, Mohammad A, Mohammadi S, Amoozgar Z, Dinarvand R. 2016. Chemically crosslinked nanogels of PEGylated poly ethyleneimine (L-histidine substituted) synthesized via metal ion coordinated self-assembly for delivery of methotrexate: Cytocompatibility, cellular delivery and antitumor activity in resistant cells. Mater. Sci. Eng. C 62, 897–907. DOI: 10.1016/j.msec.2016.02.045.
Sari D, Cairns J, Safitri A, Fatchiyah, F. 2019. Virtual prediction of the Delphinidin-3-O-glucoside and Peonidin-3-O-glucoside as anti-inflammatory of TNF- ? signaling. Acta Inform. Medica 27, 152–157. DOI: 10.5455/aim.2019.27.152-157.
Saudah, Zumaidar, Darusman, Fitmawati, Roslim DI, Ernilasari. 2022. Ethnobotanical knowledge of Etlingera elatior for medicinal and food uses among ethnic groups in Aceh Province, Indonesia. Biodiversitas 23, 4361–4370. DOI: 10.13057/biodiv/d230862.
Setyowati FM, Wardah W. 2007. Diversity of medicinal plant by Talang Mamak tribe in surrounding of Bukit Tiga Puluh National Park, Riau. Biodiversitas J. Biol. Divers. 8, 228–232. DOI: 10.13057/biodiv/d080313.
Shalas AF, Khasanah U, Adianingsih OR, Raharjaa KR, Khansa N, Maula RA, Destian NC, Lestari SW. 2021. Ethnomedicine study of Tengger people of Ngadas Village in Malang, East Java, Indonesia: In search of antimicrobial plants. J. Young Pharm. 13, 97–106. DOI: 10.5530/jyp.2021.13.22.
Singh S, Ghosh SK, Mandal MK, Masih A, Bhat HR. 2021. 1, 3, 5?Triazine: A versatile pharmacophore with diverse biological activities. Arch. Pharm. (Weinheim). 1–23. DOI: 10.1002/ardp.202000363.
Song MJ, Kim H, Lee BY, Brian H, Park CH, Hyun CW. 2014. Analysis of traditional knowledge of medicinal plants from residents in Gayasan National Park (Korea). J. Ethnobiol. Ethnomed. 10, 74. DOI: 10.1186/1746-4269-10-74.
Sribalan R, Kirubavathi M, Banuppriya G, Padmini V. 2015. Synthesis and biological evaluation of new symmetric curcumin derivatives. Bioorg. Med. Chem. Lett. DOI: 10.1016/j.bmcl.2015.07.088.
Stefanucci A, Novellino E, Costante R, Mollica A. 2014. Pyroglutamic acid derivatives: Building blocks for drug discovery. Heterocycles 89, 1801–1825. DOI: 10.3987/REV-14-800.
Sujarwo W, Arinasa IBK, Salomone F, Caneva G, Fattorini S. 2014. Cultural erosion of Balinese indigenous knowledge of food and nutraceutical plants. Econ. Bot. 68, 426–437. DOI: 10.1007/s12231-014-9288-1.
Sun H, Zhang P, Zhu Y, Lou Q, He S. 2018. Antioxidant and prebiotic activity of five peonidin-based anthocyanins extracted from purple sweet potato (Ipomoea batatas ( L .) Lam .). Sci. Rep. 1–12. DOI: 10.1038/s41598-018-23397-0.
Susanti R, Zuhud EAM. 2019. Traditional ecological knowledge and biodiversity conservation: The medicinal plants of the Dayak Krayan people in Kayan Mentarang National Park, Indonesia. Biodiversitas 20, 2764–2779. DOI: 10.13057/biodiv/d20094.
Susiarti S, Rahayu M, Rugayah. 2018. Diversity of Indonesian medicinal plant in the lowland forest, Bodogol and its surrounding of Mount Gede-Pangrango National Park, West Java. IOP Conf. Ser. Earth Environ. Sci. 166. DOI: 10.1088/1755-1315/166/1/012021.
Tiwari A, Mahadik KR, Gabhe SY. 2020. Medicine in drug discovery Piperine: A comprehensive review of methods of isolation, purification, and biological properties. Med. Drug Discov. 7, 100027. DOI: 10.1016/j.medidd.2020.100027.
Tomasini S, Theilade I. 2019. Local knowledge of past and present uses of medicinal plants in Prespa National Park, Albania. Econ. Bot. 73, 217–232. DOI: 10.1007/s12231-019-09454-3.
Utaminingrum W, Nofrianti, Hartanti D. 2022. Diversity and use of medicinal plants for traditional women’s health care in Northern Banyumas, Indonesia. Biodiversitas 23, 1970–1976. DOI: 10.13057/biodiv/d230431.
van Wyk B, Wink M. 2017. Medicinal Plants of the World, 2nd ed. CABI, Boston.
Vardanyan R. 2017. Piperidine-Based Drug Discovery. Elsevier Ltd.
Wang C, Zhou Q, Wu ST. 2022. Scopolin obtained from Smilax china L. against hepatocellular carcinoma by inhibiting glycolysis: A network pharmacology and experimental study. J. Ethnopharmacol. 296, 115469. DOI: 10.1016/j.jep.2022.115469.
Wang G, Wang J, Liu W, Nisar MF, El-esawi MA, Wan C. 2021. Biological activities and chemistry of triterpene saponins from Medicago species: An update review. Evidence-Based Complement. Altern. Med. 2021, 11. DOI: 10.1155/2021/6617916.
Wang JHZ. 2019. National parks in China: Parks for people or for the nation?. Land use policy 81, 825–833. DOI: 10.1016/j.landusepol.2018.10.034.
Wei HE, Anran Z, Jiajia ZOU, Xuan LUO, Xiao LIN, Lisheng W, Cuiwu LIN. 2018. Synthesis, in vitro coagulation activities and molecular docking studies on three L-Histidine amide derivatives. Chem. Res. Chinese Univ. 34, 90–94. DOI: 10.1007/s40242-018-7184-4.
Xing L, Liang L, Yun Z, Lei H, Jian Y, Dong Z, Ping G. 2019. Chemical constituents from Sorbus aucuparia cell suspension treated with yeast and their antifungal activity. Nat. Prod. Res. Dev. 31, 2071–2076.
Yudiyanto Y, Hakim N, Wakhidah AZ. 2022. Ethnobotany of medicinal plants from Lampung Tribe around Way Kambas National Park, Indonesia. Nusant. Biosci. 14, 84–94. DOI: 10.13057/nusbiosci/n140111.
Zatout F, Benarba B, Bouazza A, Babali B, Bey NN, Morsli A. 2021. Ethnobotanical investigation on medicinal plants used by local populations in Tlemcen National Park (extreme North West Algeria). Mediterr. Bot. 42, 1–12. DOI: 10.5209/MBOT.69396.
Zhang J, Yang YN, Feng ZM, Yuan X, Zhang X, Jiang JS, Zhang PC. 2022. The triterpenoids and sesquiterpenoids from the plant of Agrimonia pilosa. Fitoterapia 157, 105104. DOI: 10.1016/j.fitote.2021.105104.
Zhu Q, Lang L, Wang Y, Zhang D. 2022. Triterpenoids from the fruits of wild species of Crataegus scabrifolia and their lipid-lowering activities. Russ. J. Bioorganic Chem. 48, 1291–1298. DOI: 10.1134/S1068162022060292.
Zygmunt M, Ch?on-Rzepa G, Sapa J, Paw?owski M. 2015. Analgesic activity of new 8-methoxy-1,3-dimethyl-2,6-dioxo- purin-7-yl derivatives with carboxylic, ester or amide moieties. Pharmacol. Reports 67, 9–16. DOI: 10.1016/j.pharep.2014.07.018.
Most read articles by the same author(s)
- WEKA SIDHA BHAGAWAN, ARUM SUPROBORINI, DENTHA LORENZA PRASTYA PUTRI, AISSYAH NURFATMA, ROY TRI PUTRA, Ethnomedicinal study, phytochemical characterization, and pharmacological confirmation of selected medicinal plant on the northern slope of Mount Wilis, East Java, Indonesia , Biodiversitas Journal of Biological Diversity: Vol. 23 No. 8 (2022)