Potential of prospective medicinal plants of Rhizophoraceae from North Kalimantan, Indonesia

Article Sidebar

PDF
Published: 2023-03-23
DOI: https://doi.org/10.13057/biodiv/d240303
Article Metrics

Abstract Views: 458
File Views: 1

Main Article Content

SAAT EGRA
United Graduate School of Agriculture Sciences, Gifu University, Yanagido 501-1193 Gifu, Japan
HARLINDA KUSPRADINI
Faculty of Forestry, Universitas Mulawarman. Jl. Penajam, Kampus Gunung Kelua, Samarinda 75119, East Kalimantan, Indonesia
IRAWAN WIJAYA KUSUMA
Faculty of Forestry, Universitas Mulawarman. Jl. Penajam, Kampus Gunung Kelua, Samarinda 75119, East Kalimantan, Indonesia
IRMANIDA BATUBARA
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Tropical Biopharmaca Research Center, Institut Pertanian Bogor. Jl. Meranti, Kampus IPB Dramaga, Bogor 16680, West Java, Indonesia
IMRA
Faculty of Fishery, Universitas Borneo Tarakan. Jl. Amal Lama No. 1, Bulungan 77123, North Kalimantan, Indonesia
NURJANNAH
Faculty of Agriculture, Universitas Borneo Tarakan. Jl. Amal Lama No. 1, Bulungan 77123, North Kalimantan, Indonesia
ETTY WAHYUNI
Faculty of Agriculture, Universitas Borneo Tarakan. Jl. Amal Lama No. 1, Bulungan 77123, North Kalimantan, Indonesia
KOSEI YAMAUCHI
Faculty of Applied Biological Sciences, Gifu University. 1-1 Yanagido 501-1193 Gifu, Japan
TOHRU MITSUNAGA ♥
Faculty of Applied Biological Sciences, Gifu University. 1-1 Yanagido 501-1193 Gifu, Japan

Abstract

Abstract. Egra S, Kuspradini H, Kusuma IW, Batubara I, Imra, Nurjannah, Wahyuni E, Yamauchi K, Mitsunaga T. 2023. Potential of prospective medicinal plants of Rhizophoraceaefrom North Kalimantan, Indonesia. Biodiversitas 24: 1346-1355. The abundance of mangrove forests in the equatorial region necessitates proper management, including the sustainable use of plant parts for functional products such as food, medicine, etc. This study aimed to assess the medicinal potential of five mangrove plants through phytochemical analysis, antibacterial assays against Streptococcus sobrinus, DPPH free radicals, and toxicity assay using Artemia salina L., Bruguiera parviflora(Roxb.) Wight and Arn. ex Griff, Bruguiera cylindrica(L.) Blume, Ceriops tagal(Perr.). The plants used were Ceriops tagal (Perr.) C.B. Rob, Rhizophora mucronata Poir, and Rhizophora apiculata Blume. Plant samples were extracted with n-hexane, ethyl acetate, and methanol in that order, and then the obtained plant extracts were subjected to various assays. The results showed that B. cylindrica wood and C. tagal leaf extract had the highest antibacterial activity, with more than 50% relative inhibition. The C. tagal leaf methanolic extract had the highest antioxidant activity, by 91% relative inhibition. Followed by R. mucronata wood ethyl acetate extract and B. parviflora leaf methanolic extract, with 87% and 86%, respectively. The highest value in the cytotoxicity assay was discovered in the B. cylindrica in the very strong category with an LC50value of 22.9 µg/mL. The present study revealed the potential of mangrove plant extracts to have strong antibacterial, cytotoxic, and antioxidant properties.

Article Details

Issue

Vol. 24 No. 3 (2023)

Section

Articles
Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

References

Abubakar, S., Kadir, asykhur A., Wibowo, E. S., & Nebuchadnezzar Akbar. (2019). MANFAAT MANGROVE BAGI PERUNTUKAN SEDIAAN FARMASITIKA DI DESA MAMUYA KECAMATAN GALELA TIMUR KABUPATEN HALMAHERA TIMUR (TINJAUAN ETNOFARMAKOLOGIS). Jurnal Enggano, 4(1), 12–25. https://core.ac.uk/download/pdf/228580043.pdf

Alara, O. R., Abdurahman, N. H., & Ukaegbu, C. I. (2021). Extraction of phenolic compounds: A review. In Current Research in Food Science (Vol. 4). https://doi.org/10.1016/j.crfs.2021.03.011

Badarinath, A. V., Mallikarjuna Rao, K., Madhu Sudhana Chetty, C., Ramkanth, S., Rajan, T. V. S., & Gnanaprakash, K. (2010). A review on In-vitro antioxidant methods: Comparisions, correlations and considerations. In International Journal of PharmTech Research (Vol. 2, Issue 2).

Briaud, P., & Carroll, R. K. (2020). Extracellular vesicle biogenesis and functions in gram-positive bacteria. In Infection and Immunity (Vol. 88, Issue 12). https://doi.org/10.1128/IAI.00433-20

Cole, T. J., Short, K. L., & Hooper, S. B. (2019). The science of steroids. Seminars in Fetal and Neonatal Medicine, 24(3). https://doi.org/10.1016/j.siny.2019.05.005

Conrads, G., de Soet, J. J., Song, L., Henne, K., Sztajer, H., Wagner-Döbler, I., & Zeng, A. P. (2014). Comparing the cariogenic species Streptococcus sobrinus and S. mutans on whole genome level. In Journal of Oral Microbiology (Vol. 6, Issue 1). https://doi.org/10.3402/jom.v6.26189

Das, A. K., Islam, M. N., Faruk, M. O., Ashaduzzaman, M., & Dungani, R. (2020). Review on tannins: Extraction processes, applications and possibilities. In South African Journal of Botany (Vol. 135). https://doi.org/10.1016/j.sajb.2020.08.008

Debnath, B., Singh, W. S., Das, M., Goswami, S., Singh, M. K., Maiti, D., & Manna, K. (2018). Role of plant alkaloids on human health: A review of biological activities. In Materials Today Chemistry (Vol. 9). https://doi.org/10.1016/j.mtchem.2018.05.001

Douglas R. Green. (2022). Nonapoptotic cell death pathways. Cshperspectives.Cshlp.Org. https://cshperspectives.cshlp.org/content/14/11/a041079.short

Hagerman, A. E., Riedl, K. M., Jones, G. A., Sovik, K. N., Ritchard, N. T., Hartzfeld, P. W., & Riechel, T. L. (1998). High Molecular Weight Plant Polyphenolics (Tannins) as Biological Antioxidants. Journal of Agricultural and Food Chemistry, 46(5). https://doi.org/10.1021/jf970975b

Kedare, S. B., & Singh, R. P. (2011). Genesis and development of DPPH method of antioxidant assay. In Journal of Food Science and Technology (Vol. 48, Issue 4). https://doi.org/10.1007/s13197-011-0251-1

Khan, M. I., Bouyahya, A., Hachlafi, N. E. L., Menyiy, N. El, Akram, M., Sultana, S., Zengin, G., Ponomareva, L., Shariati, M. A., Ojo, O. A., Dall’Acqua, S., & Elebiyo, T. C. (2022). Anticancer properties of medicinal plants and their bioactive compounds against breast cancer: a review on recent investigations. Environmental Science and Pollution Research, 29(17), 24411–24444. https://doi.org/10.1007/S11356-021-17795-7

Kurniawan, B., & Aryana, W. F. (2015). Binahong (Cassia Alata L) As Inhibitor Of Escherichia Coli Growth. Faculty of Medicine Lampung University, 4(4).

Li, H. fang, Li, L. juan, Ji, L. min, Peng, X. wu, & Li, W. (2019). The extraction ability and mechanism in extraction lithium by several organic extractants. Chemical Physics Letters, 733. https://doi.org/10.1016/j.cplett.2019.136668

Liu, Z., Ren, Z., Zhang, J., Chuang, C. C., Kandaswamy, E., Zhou, T., & Zuo, L. (2018). Role of ROS and nutritional antioxidants in human diseases. In Frontiers in Physiology (Vol. 9, Issue MAY). https://doi.org/10.3389/fphys.2018.00477

Mahmud, & Wahyudi. (2014). Pemanfaatan Vegetasi Mangrove sebagai Obat-obatan Tradisional pada Lima Suku di Papua. Journal of Biota, 19(1). https://doi.org/10.24002/biota.v19i1.448

Nebula, M., Harisankar, H. S., & Chandramohanakumar, N. (2013). Metabolites and bioactivities of Rhizophoraceae mangroves. Natural Products and Bioprospecting, 3(5), 207–232. https://doi.org/10.1007/S13659-013-0012-0/METRICS

Patel, K., Panchal, N., & Ingle, P. (2019). Techniques Adopted for Extraction of Natural Products Extraction Methods: Maceration, Percolation, Soxhlet Extraction, Turbo distillation, Supercritical Fluid Extraction. International Journal of Advanced Research in Chemical Science, 6(4). https://doi.org/10.20431/2349-0403.0604001

Ramalingam, V., & Rajaram, R. (2018). Enhanced antimicrobial, antioxidant and anticancer activity of Rhizophora apiculata: An experimental report. 3 Biotech, 8(4), 200. https://doi.org/10.1007/s13205-018-1222-2

Ridlo, A., Pramesti, R., Koesoemadji, K., Supriyantini, E., & Soenardjo, N. (2017). Aktivitas Antioksidan Ekstrak Daun Mangrove Rhizopora mucronata. BULETIN OSEANOGRAFI MARINA, 6(2). https://doi.org/10.14710/buloma.v6i2.16555

Sanchez, S., & Demain, A. L. (2019). Secondary metabolites. In Comprehensive Biotechnology. https://doi.org/10.1016/B978-0-444-64046-8.00012-4

Sawitri, R., Bismark, M., & Karlina, E. (2013). EKOSISTEM MANGROVE SEBAGAI OBYEK WISATA ALAM DI KAWASAN KONSERVASI MANGROVE DAN BEKANTAN DI KOTA TARAKAN. Jurnal Penelitian Hutan Dan Konservasi Alam, 2013(3). https://doi.org/10.20886/jphka.2013.10.3.297-314

Sepahpour, S., Selamat, J., Manap, M. Y. A., Khatib, A., & Razis, A. F. A. (2018). Comparative analysis of chemical composition, antioxidant activity and quantitative characterization of some phenolic compounds in selected herbs and spices in different solvent extraction systems. Molecules, 23(2). https://doi.org/10.3390/molecules23020402

Shimizu, K., Kondo, R., Sakai, K., Takeda, N., Nagahata, T., & Oniki, T. (2001). Novel vitamin E derivative with 4-substituted resorcinol moiety has both antioxidant and tyrosinase inhibitory properties. Lipids, 36(12). https://doi.org/10.1007/s11745-001-0847-9

Sivaperumal, P., Ramasamy, P., & Inbaneson, S. (2010). Screening of antibacterial activity of mangrove leaf bioactive compounds against antibiotic resistant clinical isolates. World J Fish Mar Sci, 2(5), 348–353.

Sormin, R. B. D., Nendissa, D. M., Mailoa, M. N., Rieuwpassa, F., & Wenno, M. R. (2021). Antibacterial activity of Rhizophora apiculata extract originated from Inner Ambon Bay against selected pathogen bacteria. IOP Conference Series: Earth and Environmental Science, 797(1). https://doi.org/10.1088/1755-1315/797/1/012017

Syawal, H., Hakim, L., & Effendi, I. (2020). Phytochemical analysis of rhizophora apiculata leaf extract and its inhibitory action against staphylococcus aureus, aeromonas hydrophila and pseudomonas aeruginosa. AACL Bioflux, 13(4), 2242–2249.

Widadi, Rahayu, I., Purwaningsih, S., & Wientarsih, I. (2014). Toxicological Evaluation of Syrup from Rhizophora mucronata Hypocotyls Ethanolic Extract in Sprague-Dawley rats. Global Journal of Biology, Agriculture, and Health Sciences, 1(2), 2085–9449.

Zhang, Q. W., Lin, L. G., & Ye, W. C. (2018). Techniques for extraction and isolation of natural products: A comprehensive review. In Chinese Medicine (United Kingdom) (Vol. 13, Issue 1). https://doi.org/10.1186/s13020-018-0177-x

Most read articles by the same author(s)

1 2 3 > >>