Potential of prospective medicinal plants of Rhizophoraceae from North Kalimantan, Indonesia
##plugins.themes.bootstrap3.article.sidebar##
Issue
Section
Articles
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
##plugins.themes.bootstrap3.article.main##
Abstract
Abstract. Egra S, Kuspradini H, Kusuma IW, Batubara I, Imra, Nurjannah, Wahyuni E, Yamauchi K, Mitsunaga T. 2023. Potential of prospective medicinal plants of Rhizophoraceaefrom North Kalimantan, Indonesia. Biodiversitas 24: 1346-1355. The abundance of mangrove forests in the equatorial region necessitates proper management, including the sustainable use of plant parts for functional products such as food, medicine, etc. This study aimed to assess the medicinal potential of five mangrove plants through phytochemical analysis, antibacterial assays against Streptococcus sobrinus, DPPH free radicals, and toxicity assay using Artemia salina L., Bruguiera parviflora(Roxb.) Wight and Arn. ex Griff, Bruguiera cylindrica(L.) Blume, Ceriops tagal(Perr.). The plants used were Ceriops tagal (Perr.) C.B. Rob, Rhizophora mucronata Poir, and Rhizophora apiculata Blume. Plant samples were extracted with n-hexane, ethyl acetate, and methanol in that order, and then the obtained plant extracts were subjected to various assays. The results showed that B. cylindrica wood and C. tagal leaf extract had the highest antibacterial activity, with more than 50% relative inhibition. The C. tagal leaf methanolic extract had the highest antioxidant activity, by 91% relative inhibition. Followed by R. mucronata wood ethyl acetate extract and B. parviflora leaf methanolic extract, with 87% and 86%, respectively. The highest value in the cytotoxicity assay was discovered in the B. cylindrica in the very strong category with an LC50value of 22.9 µg/mL. The present study revealed the potential of mangrove plant extracts to have strong antibacterial, cytotoxic, and antioxidant properties.
##plugins.themes.bootstrap3.article.details##
References
Abubakar, S., Kadir, asykhur A., Wibowo, E. S., & Nebuchadnezzar Akbar. (2019). MANFAAT MANGROVE BAGI PERUNTUKAN SEDIAAN FARMASITIKA DI DESA MAMUYA KECAMATAN GALELA TIMUR KABUPATEN HALMAHERA TIMUR (TINJAUAN ETNOFARMAKOLOGIS). Jurnal Enggano, 4(1), 12–25. https://core.ac.uk/download/pdf/228580043.pdf
Alara, O. R., Abdurahman, N. H., & Ukaegbu, C. I. (2021). Extraction of phenolic compounds: A review. In Current Research in Food Science (Vol. 4). https://doi.org/10.1016/j.crfs.2021.03.011
Badarinath, A. V., Mallikarjuna Rao, K., Madhu Sudhana Chetty, C., Ramkanth, S., Rajan, T. V. S., & Gnanaprakash, K. (2010). A review on In-vitro antioxidant methods: Comparisions, correlations and considerations. In International Journal of PharmTech Research (Vol. 2, Issue 2).
Briaud, P., & Carroll, R. K. (2020). Extracellular vesicle biogenesis and functions in gram-positive bacteria. In Infection and Immunity (Vol. 88, Issue 12). https://doi.org/10.1128/IAI.00433-20
Cole, T. J., Short, K. L., & Hooper, S. B. (2019). The science of steroids. Seminars in Fetal and Neonatal Medicine, 24(3). https://doi.org/10.1016/j.siny.2019.05.005
Conrads, G., de Soet, J. J., Song, L., Henne, K., Sztajer, H., Wagner-Döbler, I., & Zeng, A. P. (2014). Comparing the cariogenic species Streptococcus sobrinus and S. mutans on whole genome level. In Journal of Oral Microbiology (Vol. 6, Issue 1). https://doi.org/10.3402/jom.v6.26189
Das, A. K., Islam, M. N., Faruk, M. O., Ashaduzzaman, M., & Dungani, R. (2020). Review on tannins: Extraction processes, applications and possibilities. In South African Journal of Botany (Vol. 135). https://doi.org/10.1016/j.sajb.2020.08.008
Debnath, B., Singh, W. S., Das, M., Goswami, S., Singh, M. K., Maiti, D., & Manna, K. (2018). Role of plant alkaloids on human health: A review of biological activities. In Materials Today Chemistry (Vol. 9). https://doi.org/10.1016/j.mtchem.2018.05.001
Douglas R. Green. (2022). Nonapoptotic cell death pathways. Cshperspectives.Cshlp.Org. https://cshperspectives.cshlp.org/content/14/11/a041079.short
Hagerman, A. E., Riedl, K. M., Jones, G. A., Sovik, K. N., Ritchard, N. T., Hartzfeld, P. W., & Riechel, T. L. (1998). High Molecular Weight Plant Polyphenolics (Tannins) as Biological Antioxidants. Journal of Agricultural and Food Chemistry, 46(5). https://doi.org/10.1021/jf970975b
Kedare, S. B., & Singh, R. P. (2011). Genesis and development of DPPH method of antioxidant assay. In Journal of Food Science and Technology (Vol. 48, Issue 4). https://doi.org/10.1007/s13197-011-0251-1
Khan, M. I., Bouyahya, A., Hachlafi, N. E. L., Menyiy, N. El, Akram, M., Sultana, S., Zengin, G., Ponomareva, L., Shariati, M. A., Ojo, O. A., Dall’Acqua, S., & Elebiyo, T. C. (2022). Anticancer properties of medicinal plants and their bioactive compounds against breast cancer: a review on recent investigations. Environmental Science and Pollution Research, 29(17), 24411–24444. https://doi.org/10.1007/S11356-021-17795-7
Kurniawan, B., & Aryana, W. F. (2015). Binahong (Cassia Alata L) As Inhibitor Of Escherichia Coli Growth. Faculty of Medicine Lampung University, 4(4).
Li, H. fang, Li, L. juan, Ji, L. min, Peng, X. wu, & Li, W. (2019). The extraction ability and mechanism in extraction lithium by several organic extractants. Chemical Physics Letters, 733. https://doi.org/10.1016/j.cplett.2019.136668
Liu, Z., Ren, Z., Zhang, J., Chuang, C. C., Kandaswamy, E., Zhou, T., & Zuo, L. (2018). Role of ROS and nutritional antioxidants in human diseases. In Frontiers in Physiology (Vol. 9, Issue MAY). https://doi.org/10.3389/fphys.2018.00477
Mahmud, & Wahyudi. (2014). Pemanfaatan Vegetasi Mangrove sebagai Obat-obatan Tradisional pada Lima Suku di Papua. Journal of Biota, 19(1). https://doi.org/10.24002/biota.v19i1.448
Nebula, M., Harisankar, H. S., & Chandramohanakumar, N. (2013). Metabolites and bioactivities of Rhizophoraceae mangroves. Natural Products and Bioprospecting, 3(5), 207–232. https://doi.org/10.1007/S13659-013-0012-0/METRICS
Patel, K., Panchal, N., & Ingle, P. (2019). Techniques Adopted for Extraction of Natural Products Extraction Methods: Maceration, Percolation, Soxhlet Extraction, Turbo distillation, Supercritical Fluid Extraction. International Journal of Advanced Research in Chemical Science, 6(4). https://doi.org/10.20431/2349-0403.0604001
Ramalingam, V., & Rajaram, R. (2018). Enhanced antimicrobial, antioxidant and anticancer activity of Rhizophora apiculata: An experimental report. 3 Biotech, 8(4), 200. https://doi.org/10.1007/s13205-018-1222-2
Ridlo, A., Pramesti, R., Koesoemadji, K., Supriyantini, E., & Soenardjo, N. (2017). Aktivitas Antioksidan Ekstrak Daun Mangrove Rhizopora mucronata. BULETIN OSEANOGRAFI MARINA, 6(2). https://doi.org/10.14710/buloma.v6i2.16555
Sanchez, S., & Demain, A. L. (2019). Secondary metabolites. In Comprehensive Biotechnology. https://doi.org/10.1016/B978-0-444-64046-8.00012-4
Sawitri, R., Bismark, M., & Karlina, E. (2013). EKOSISTEM MANGROVE SEBAGAI OBYEK WISATA ALAM DI KAWASAN KONSERVASI MANGROVE DAN BEKANTAN DI KOTA TARAKAN. Jurnal Penelitian Hutan Dan Konservasi Alam, 2013(3). https://doi.org/10.20886/jphka.2013.10.3.297-314
Sepahpour, S., Selamat, J., Manap, M. Y. A., Khatib, A., & Razis, A. F. A. (2018). Comparative analysis of chemical composition, antioxidant activity and quantitative characterization of some phenolic compounds in selected herbs and spices in different solvent extraction systems. Molecules, 23(2). https://doi.org/10.3390/molecules23020402
Shimizu, K., Kondo, R., Sakai, K., Takeda, N., Nagahata, T., & Oniki, T. (2001). Novel vitamin E derivative with 4-substituted resorcinol moiety has both antioxidant and tyrosinase inhibitory properties. Lipids, 36(12). https://doi.org/10.1007/s11745-001-0847-9
Sivaperumal, P., Ramasamy, P., & Inbaneson, S. (2010). Screening of antibacterial activity of mangrove leaf bioactive compounds against antibiotic resistant clinical isolates. World J Fish Mar Sci, 2(5), 348–353.
Sormin, R. B. D., Nendissa, D. M., Mailoa, M. N., Rieuwpassa, F., & Wenno, M. R. (2021). Antibacterial activity of Rhizophora apiculata extract originated from Inner Ambon Bay against selected pathogen bacteria. IOP Conference Series: Earth and Environmental Science, 797(1). https://doi.org/10.1088/1755-1315/797/1/012017
Syawal, H., Hakim, L., & Effendi, I. (2020). Phytochemical analysis of rhizophora apiculata leaf extract and its inhibitory action against staphylococcus aureus, aeromonas hydrophila and pseudomonas aeruginosa. AACL Bioflux, 13(4), 2242–2249.
Widadi, Rahayu, I., Purwaningsih, S., & Wientarsih, I. (2014). Toxicological Evaluation of Syrup from Rhizophora mucronata Hypocotyls Ethanolic Extract in Sprague-Dawley rats. Global Journal of Biology, Agriculture, and Health Sciences, 1(2), 2085–9449.
Zhang, Q. W., Lin, L. G., & Ye, W. C. (2018). Techniques for extraction and isolation of natural products: A comprehensive review. In Chinese Medicine (United Kingdom) (Vol. 13, Issue 1). https://doi.org/10.1186/s13020-018-0177-x
Most read articles by the same author(s)
- SYAFRIZAL, RICO RAMADHAN , IRAWAN WIJAYA KUSUMA, SAAT EGRA, KUNIYOSHI SHIMIZU, MAMORU KANZAKI, ENOS TANGKE ARUNG, Diversity and honey properties of stingless bees from meliponiculture in East and North Kalimantan, Indonesia , Biodiversitas Journal of Biological Diversity: Vol. 21 No. 10 (2020)
- ELISA HERAWATI, RICO RAMADHAN, FARIDA ARIYANI, MARJENAH, IRAWAN WIJAYA KUSUMA, WIWIN SUWINARTI, DJUMALI MARDJI, RUDIANTO AMIRTA, ENOS TANGKE ARUNG, Phytochemical screening and antioxidant activity of wild mushrooms growing in tropical regions , Biodiversitas Journal of Biological Diversity: Vol. 22 No. 11 (2021)
- ENOS TANGKE ARUNG, WHICLIFFE FIERNALEONARDO PASEDAN, IRAWAN WIJAYA KUSUMA, MEDI HENDRA, MERY BUDIARTI SUPRIADI, Short Communication: Selected medicinal plants in East and North Kalimantan (Indonesia) against Propionibacterium acnes , Biodiversitas Journal of Biological Diversity: Vol. 18 No. 1 (2017)
- SYAMSUL HIDAYAT, ERVIZAL A.M. ZUHUD, DIDIK WIDYATMOKO, BAHRUNI, IRMANIDA BATUBARA, The commercial potential of forest trees as medicinal and health ingredients , Biodiversitas Journal of Biological Diversity: Vol. 22 No. 7 (2021)
- KARTINA KARTINA, IRMANIDA BATUBARA, HARLINDA KUSPRADINI, IRAWAN WIJAYA KUSUMA, WULAN TRI WAHYUNI, SAAT EGRA, TOHRU MITSUNAGA, Diversity of medicinal plants used for skincare by Bulungan tribe in North Kalimantan, Indonesia and its melanin biosynthesis inhibition , Biodiversitas Journal of Biological Diversity: Vol. 23 No. 3 (2022)
- DINA TIARA KUSUMAWARDHANI, DODI NANDIKA, LINA KARLINASARI, ARINANA, IRMANIDA BATUBARA, Architectural and physical properties of fungus comb from subterranean termite Macrotermes gilvus (Isoptera: Termitidae) mound , Biodiversitas Journal of Biological Diversity: Vol. 22 No. 4 (2021)
- HENNY NURHASNAWATI, REKSI SUNDU, SAPRI SAPRI, RISA SUPRININGRUM, HARLINDA KUSPRADINI, ENOS TANGKE ARUNG, Antioxidant activity, total phenolic and flavonoid content of several indigenous species of ferns in East Kalimantan, Indonesia , Biodiversitas Journal of Biological Diversity: Vol. 20 No. 2 (2019)
- RICO RAMADHAN, PREECHA PHUWAPRAISIRISAN, RUDIANTO AMIRTA, MUHAMMAD FADIL BAGAS DARMAWAN, KAUTSAR UL-HAQ, IRAWAN WIJAYA KUSUMA, HERY SUWITO, NURLITA ABDULGANI, AHMAD MUKHDLOR, SAPARWADI, The potency of selected ethnomedicinal plants from East Kalimantan, Indonesia as antidiabetic agents and free-radical scavengers , Biodiversitas Journal of Biological Diversity: Vol. 23 No. 4 (2022)
- RICO RAMADHAN, ALFINDA NOVI KRISTANTI, RUDIANTO AMIRTA, IRAWAN WIJAYA KUSUMA, PREECHA PHUWAPRAISIRISAN, MUHAMMAD TAUFIQ HAQIQI, SAPARWADI SAPARWADI, Screening for potential antidiabetes and antioxidant activities of selected plants from East Kalimantan, Indonesia , Biodiversitas Journal of Biological Diversity: Vol. 20 No. 7 (2019)
- EMILDA KUSPRANINGRUM, THOHIR LUTH, YULIATI, RACHMAD SAFA’AT, HARLINDA KUSPRADINI, Review: The conservation of Tengger indigenous people's traditional knowledge of biological natural resource?based disease treatments , Biodiversitas Journal of Biological Diversity: Vol. 21 No. 11 (2020)